Assorted, but all unpleasant, side effects happened when the doc upped my dosage. (Technically not new meds, but that made a better title.) Bad sleep followed, so my 2 other chronic conditions decided to come out and play.
@kali66 Agreed. However, once I'm accustomed to the new dosage it should be a couple of years at least with no side effects before needing to increase it again.