Travel in Ecuador often means making the effort to arrive in certain towns on market day; or the night before.
Visiting Ecuador's indigenous markets is so popular with Gringo tourists that day tours even depart from Quito; to Otavalo (Plaza de Ponchos), and Saquisili (baskets).
Riobamba and Cuenca (flowers) are further away and will most likely mean staying the night; maybe on the way south to Guayaquil.